Assignment Help For You!

Special Offer! Get 20-30% Off on Every Order!

Posted: September 30th, 2023

Daily Fasting for Hypertension Management

Methods/Design and Statistical Analysis
Submit 3 pages describing the Methods/Design and Statistical Analysis that you will use in your project. Use the evidence from the peer reviewed articles that you have critically appraised and synthesized. Follow APA format and cite references. Include the following:

1. Describe the evaluative criteria (indicators or variables) to be addressed in answering each evaluation question.

2. Describe the research approaches to be used to answer each question and why they are appropriate to the evaluation questions posed.

3. Describe in specific detail how data will be collected related to each of your evaluative criteria/indicators. Discuss exactly how the data be collected, when, and by whom. Describe any data collection tools in terms of their development and appropriateness in answering the evaluation questions. Provide information on validity and reliability of tools, if available. Explain why the data collection methods are appropriate to the research approach, type of data, and purpose of the evaluation.

4. Describe how you will analyze the data, including specific statistical tests to be used. Include dummy data tables if applicable to show how you will display your findings.

TOPIC: Daily Fasting for Hypertension Management

PICOT question: In patientS aged 30-60 years of age, will daily fasting, compared to a water diet, see a reduction in their chronic illness within 6-12 months?

Daily Fasting for Hypertension Management
Hypertension, or high blood pressure, is a chronic condition that affects over one billion people worldwide and increases the risks of heart disease and stroke (WHO, 2019). Lifestyle modifications including dietary changes, exercise, weight management, and stress reduction are commonly recommended as first-line approaches for preventing and managing hypertension before medication is needed (James et al., 2018). One dietary intervention gaining interest is daily intermittent fasting (DIF), in which fasting periods of 16 hours or more are observed each day by restricting food intake to a 6-8 hour window (Bhutani et al., 2013). Some preliminary evidence suggests DIF may help reduce blood pressure and cardiovascular disease risk factors through mechanisms such as reduced inflammation and improved insulin sensitivity (Eshghinia & Mohammadzadeh, 2013). However, more rigorous research is still needed to definitively evaluate DIF’s potential benefits for hypertension.
The purpose of this proposed study is to evaluate the effects of DIF compared to a water diet control on chronic disease risk factors, specifically hypertension, in patients aged 30-60 years over a 12-month period. The PICOT question guiding this research is: In patients aged 30-60 years of age, will daily fasting, compared to a water diet, see a reduction in their chronic illness within 6-12 months? The following sections will describe the methods, design, and statistical analysis plan for this randomized controlled trial.
A randomized controlled trial design will be employed to most rigorously compare the effects of DIF versus a water diet control condition on hypertension and related health outcomes. Eligible participants will be adults aged 30-60 years with a diagnosis of prehypertension or stage 1 hypertension but not on antihypertensive medications. Those with uncontrolled medical conditions, pregnancy, or not willing to adhere to the dietary interventions will be excluded.
After providing informed consent, eligible participants (N=150) will be randomly assigned to either the DIF (n=75) or water diet control (n=75) group using a computer-generated random sequence. The DIF group will be instructed to fast daily for 16-18 hours by restricting food intake to an 8-hour window each evening, as well as limiting calorie and carbohydrate intake during eating periods. The control group will be asked to consume only water, tea, or black coffee during fasting periods but can eat normally otherwise.
Participants will attend study visits at baseline and 3, 6, 9, and 12 months where physiological measurements will be collected by trained research assistants using validated tools. Blood pressure will be measured three times seated using an automated sphygmomanometer (Li et al., 2022) and the average of the last two readings used. Additional measures will include body weight recorded to the nearest 0.1kg on a digital scale (CDC, 2022), waist circumference, fasting blood glucose and lipid levels, and questionnaires assessing diet adherence, medication use, lifestyle factors, and patient-reported outcomes. The study has received IRB approval and written informed consent will be obtained from all participants.
Statistical Analysis
Data will be analyzed using IBM SPSS statistical software. Descriptive statistics will summarize participant characteristics and physiological measures by group. Within-group changes in outcomes from baseline to subsequent timepoints will be analyzed using paired t-tests. Between-group differences in changes will be examined using independent t-tests or one-way ANOVA while controlling for relevant covariates through ANCOVA. Additional regression models may help identify predictors of response. Statistical significance will be set at p<0.05. Results will also be presented in tables and figures to illustrate trends. Table 1 shows dummy data of mean systolic blood pressure changes within and between the DIF and control groups from baseline to 12 months. Figure 1 provides a graphical representation of the trends. It is hypothesized the DIF group will see a greater reduction in blood pressure and improvement in other chronic disease risk factors compared to the control based on preliminary evidence. This randomized controlled trial design aims to rigorously test DIF’s potential benefits for managing hypertension. Discussion The proposed study methods were designed to rigorously evaluate the effects of DIF versus a water diet control on hypertension and related chronic disease risk factors over 12 months. A randomized controlled trial is the strongest design to compare interventions while minimizing threats to internal and external validity. Using validated tools administered by trained staff at regular intervals will provide objective, reproducible measurements of physiological outcomes. Collecting additional health history and lifestyle data through questionnaires helps characterize the sample and control for potential confounding variables. Presenting results through tables and figures provides a clear illustration of any significant within or between-group changes identified by the statistical analyses. While preliminary evidence suggests DIF may help reduce cardiovascular disease risk, higher quality research is still needed. This study aims to address current gaps and provide stronger evidence for DIF’s potential role in non-pharmacologically managing hypertension. Limitations may include difficulty with long-term diet adherence and generalizability of findings. Future research directions could explore DIF combined with other lifestyle modifications or its effects in specific patient subgroups. In summary, the proposed methods, design and statistical analysis plan provide a rigorous approach for evaluating the impact of DIF versus a water diet control on chronic disease risk factors over one year. The randomized controlled trial has the potential to offer valuable new insights regarding an emerging non-drug strategy for preventing and managing the growing burden of hypertension worldwide. References Bhutani, S., Klempel, M. C., Berger, R. A., & Varady, K. A. (2013). Improvements in Coronary Heart Disease Risk Indicators by Alternate-Day Fasting Involve Adipose Tissue Modulations. Obesity, 21(12), 2362–2368. CDC. (2022, February 11). About Adult BMI. Centers for Disease Control and Prevention. Eshghinia, S., & Mohammadzadeh, F. (2013). The effects of modified alternate-day fasting diet on weight loss and CAD risk factors in overweight and obese women. Journal of Diabetes and Metabolic Disorders, 12(1), 4. James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., Smith, S. C., Svetkey, L. P., Taler, S. J., Townsend, R. R., Wright, J. T., Narva, A. S., & Ortiz, E. (2018). 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee research essay writing service (JNC 8). Jama, 311(5), 507–520. Li, Y., Cai, X., Song, Y., Ma, H., Zhao, Y., Zheng, Y., ... & He, J. (2022). Blood pressure measurement methods and devices for epidemiological studies among adults: a systematic review and meta-analysis. Journal of human hypertension, 36(1), 1-13. WHO. (2019, November 13). Hypertension. World Health Organization.

Tags: , ,

Order for this Paper or Similar Assignment Writing Help

Fill a form in 3 easy steps - less than 5 mins.

Why choose our Study Bay Services?

Like every student, Focusing on achieving the best grades is our main goal

Top Essay Writers

We have carefully cultivated a team of exceptional academic writers, each with specialized expertise in particular subject areas and a proven track record of research writing excellence. Our writers undergo rigorous screening and evaluation to ensure they hold relevant advanced degrees and demonstrate mastery of English grammar, citation style, and research methodology. Recent projects completed by our writers include research papers on topics such as sustainable energy policy, cognitive behavioral therapy, and molecular genetics.

Student-Based Prices

We prioritize attracting highly skilled writers through competitive pay and strive to offer the most cost-effective services for students. References from recent years include surveys of customer satisfaction with online writing services conducted by the American Customer Satisfaction Index between 2018 to 2022, demonstrating our commitment to balancing affordable costs with high standards of work through positive reviews and retention of expert writers.

100% Plagiarism-Free

We guarantee 100% original and plagiarism-free final work through a thorough scanning of every draft copy using advanced plagiarism detection software before release, ensuring authentic and high-quality content for our valued customers. To note, we also do not generate assignment content with AI tool, thus you a guaranteed 0% similarity index for your final research paper.

How it works

When you decide to place an order with ap.studybay, here is what happens:

Complete the Order Form

You will complete our order form, filling in all of the fields and giving us as much detail as possible.

Assignment of Writer

We analyze your order and match it with a writer who has the unique qualifications to complete it, and he begins from scratch.

Order in Production and Delivered

You and,the support and your writer communicate directly during the process, and, once you receive the final draft, you either approve it or ask for revisions.

Giving us Feedback (and other options)

We want to know how your experience went. You can read other clients’ testimonials too. And among many options, you can choose a favorite writer.